Hepatology Services at Nottingham Road Clinic provide specialist assessment and management of conditions affecting the liver, biliary system and related metabolic and systemic processes. Liver disease is common, often under-recognised in its early stages, and may progress silently before symptoms become apparent. Timely identification and appropriate management are essential to prevent long-term complications, including cirrhosis, liver failure and hepatocellular carcinoma.
Liver disorders arise from a wide range of causes, including metabolic conditions, alcohol-related liver disease, viral hepatitis, autoimmune disease, medication toxicity and genetic predisposition. Liver dysfunction frequently coexists with other medical conditions such as obesity, diabetes, cardiovascular disease and inflammatory disorders, requiring a comprehensive and coordinated approach to care.
The service is consultant led, delivered by clinicians with expertise in hepatology and general gastroenterology. Assessment is structured, evidence based and aligned with UK clinical guidance. Care focuses on accurate diagnosis, disease staging, risk stratification and development of an individualised management plan. Access to imaging, laboratory diagnostics and multidisciplinary referral supports safe decision-making and ongoing monitoring.
Hepatology Services adopt a holistic approach, recognising the interaction between liver health, lifestyle factors, mental wellbeing and comorbid disease. Where appropriate, care interfaces with NHS hepatology services to support escalation of care or access to specialist interventions while maintaining continuity for patients and referrers.
Hepatology Services at Nottingham Road Clinic provide specialist assessment and management of conditions affecting the liver, biliary system and related metabolic and systemic processes. Liver disease is common, often under-recognised in its early stages, and may progress silently before symptoms become apparent. Timely identification and appropriate management are essential to prevent long-term complications, including cirrhosis, liver failure and hepatocellular carcinoma.
Liver disorders arise from a wide range of causes, including metabolic conditions, alcohol-related liver disease, viral hepatitis, autoimmune disease, medication toxicity and genetic predisposition. Liver dysfunction frequently coexists with other medical conditions such as obesity, diabetes, cardiovascular disease and inflammatory disorders, requiring a comprehensive and coordinated approach to care.
The service is consultant led, delivered by clinicians with expertise in hepatology and general gastroenterology. Assessment is structured, evidence based and aligned with UK clinical guidance. Care focuses on accurate diagnosis, disease staging, risk stratification and development of an individualised management plan. Access to imaging, laboratory diagnostics and multidisciplinary referral supports safe decision-making and ongoing monitoring.
Hepatology Services adopt a holistic approach, recognising the interaction between liver health, lifestyle factors, mental wellbeing and comorbid disease. Where appropriate, care interfaces with NHS hepatology services to support escalation of care or access to specialist interventions while maintaining continuity for patients and referrers.
Hepatology Services are suitable for adults requiring specialist assessment of abnormal liver tests, suspected or established liver disease, or liver-related symptoms that warrant investigation beyond primary care.
Typical presentations include persistently abnormal liver blood tests, fatty liver detected on imaging, unexplained fatigue, right upper quadrant discomfort, jaundice or pruritus. Patients may also be referred following incidental imaging findings, abnormal fibrosis assessments or concern about alcohol-related or metabolic liver disease.
Specialist input is particularly important where there is diagnostic uncertainty, evidence of progressive disease, risk of fibrosis or cirrhosis, or where comorbid conditions complicate management. Patients with viral hepatitis, autoimmune liver disease or hereditary liver conditions also benefit from consultant-led assessment and structured follow-up.
The service supports both self-pay and insured patients. Referrers include GPs and other specialists seeking clarification of abnormal results, guidance on risk stratification, or shared care planning in conjunction with NHS services.
Hepatology Services assess and manage a broad spectrum of liver-related conditions, recognising that early disease may be asymptomatic and detected only through investigation.
Fatty liver disease
This includes metabolic associated fatty liver disease and alcohol-related liver disease. Patients may present with abnormal liver enzymes or imaging findings. Risk factors include obesity, diabetes, dyslipidaemia and alcohol intake. Disease severity ranges from simple steatosis to advanced fibrosis and cirrhosis.
Alcohol-related liver disease
Assessment focuses on disease staging, identification of complications and coordinated management that addresses both liver health and alcohol dependence, where relevant.
Viral hepatitis
Chronic hepatitis B or C may be identified through blood testing or risk-based screening. Specialist assessment guides staging, monitoring and referral for antiviral therapy where appropriate.
Autoimmune and cholestatic liver disease
Conditions such as autoimmune hepatitis, primary biliary cholangitis and primary sclerosing cholangitis require careful evaluation, long-term monitoring and coordination with specialist services.
Cirrhosis and chronic liver disease
Patients with established cirrhosis or advanced fibrosis require structured surveillance for complications such as portal hypertension, ascites and hepatocellular carcinoma.
Red-flag features
Jaundice, unexplained weight loss, gastrointestinal bleeding, rapidly worsening liver function, confusion or fluid retention are prioritised for urgent assessment and onward referral.
Assessment begins with detailed history taking, focusing on symptom progression, alcohol intake, metabolic risk factors, medication use, family history and relevant exposures. The impact of symptoms on daily life and associated comorbidities is explored.
Physical examination includes assessment for stigmata of chronic liver disease, abdominal examination and evaluation for complications such as ascites or peripheral oedema where indicated.
Diagnostic pathways follow national guidance. Investigations may include comprehensive liver blood tests, viral serology, autoimmune and metabolic screening and fibrosis assessment. Imaging such as ultrasound, CT or MRI is used to assess liver architecture and exclude focal pathology. Tests are selected purposefully to inform diagnosis, staging and management.
Clinical reasoning integrates biochemical, imaging and clinical findings to define disease aetiology, severity and prognosis, supporting clear management recommendations.
Management is tailored to diagnosis, disease stage and individual risk factors, with an emphasis on preventing progression and managing complications.
Conservative and medical management
Lifestyle modification, optimisation of metabolic risk factors and medication review are central to management of many liver conditions. Disease-specific medical therapies are initiated or coordinated where indicated, in line with UK guidance.
Treatment of underlying causes
Where liver disease is driven by viral, autoimmune or metabolic processes, targeted treatment pathways are followed, often in collaboration with NHS specialist services.
Monitoring and follow-up
Ongoing surveillance for disease progression and complications is a key component of care. Follow-up plans are clearly defined, with attention to blood test monitoring, imaging and safety considerations.
Escalation and referral
Patients requiring advanced investigation, transplantation assessment or specialist interventions are referred promptly through established NHS pathways, with continuity of care maintained.
Hepatology Services work closely with radiology to support diagnostic imaging and surveillance. Collaboration with dietetic, mental health and addiction services may be appropriate, particularly in metabolic or alcohol-related liver disease.
Primary care plays a crucial role in long-term monitoring, lifestyle support and shared care prescribing. Clear communication supports safe ongoing management.
Where complex disease or complications are identified, referral to NHS hepatology, gastroenterology or surgical services is coordinated to ensure timely access to specialist care.
Appointments are structured to allow thorough review of history, test results and symptom burden. Patients are encouraged to bring previous blood test reports, imaging results and a current medication list.
During the consultation, findings are discussed clearly, including explanation of liver test abnormalities, diagnosis and disease stage. Further investigations or management options are outlined in a transparent and supportive manner.
A personalised care plan is agreed, covering treatment recommendations, lifestyle advice, follow-up and any onward referrals. Written correspondence is shared with the referrer and GP.
Do abnormal liver blood tests always indicate serious disease
Not always. Many abnormalities are mild or reversible, but assessment is important to identify underlying causes.
Can fatty liver disease be reversed
In many cases, early fatty liver disease can improve with appropriate lifestyle changes and risk factor management.
Is alcohol the only cause of liver disease
No. Metabolic, autoimmune, viral and genetic conditions are common causes of liver disease.
Will I need a liver biopsy
Most patients do not require biopsy. Non-invasive tests and imaging are often sufficient, but biopsy may be recommended in selected cases.
Can liver disease progress without symptoms
Yes. Many liver conditions progress silently, which is why investigation and monitoring are important.
Do you work with NHS liver services
Yes. Care is coordinated with NHS hepatology services where advanced treatment or specialist intervention is required.
To book an appointment or discuss which clinician you should see first:
Phone: 01623 624137
Location: Nottingham Road Clinic, 195 Nottingham Road Mansfield NG18 4AA
